Comments on: Are you a cat genome person or a dog genome person? http://www.genomicron.evolverzone.com/2007/11/are-you-cat-genome-person-or-dog-genome/ Sun, 05 Feb 2012 06:46:45 -0700 hourly 1 http://wordpress.org/?v=3.3.1 By: VWXYNot? http://www.genomicron.evolverzone.com/2007/11/are-you-cat-genome-person-or-dog-genome/comment-page-1/#comment-432 VWXYNot? Fri, 02 Nov 2007 19:08:00 +0000 http://www.genomicron.evolverzone.com/2007/11/are-you-a-cat-genome-person-or-a-dog-genome-person/#comment-432 Ah, someone else who goes straight to the TE section of new genome sequence papers!<br/><br/>BTW, I'm going to have to go and look up megabats now. I'm intrigued. Ah, someone else who goes straight to the TE section of new genome sequence papers!

BTW, I’m going to have to go and look up megabats now. I’m intrigued.

]]> By: Keith Robison http://www.genomicron.evolverzone.com/2007/11/are-you-cat-genome-person-or-dog-genome/comment-page-1/#comment-431 Keith Robison Fri, 02 Nov 2007 13:55:00 +0000 http://www.genomicron.evolverzone.com/2007/11/are-you-a-cat-genome-person-or-a-dog-genome-person/#comment-431 With sequencing costs falling so rapidly for a draft genome, I'd probably vote to go for very broad coverage of as many genomes as possible. A lot of information can be gleaned from low-pass information, and the finishing will be much cheaper tomorrow than it is today.<br/><br/>The recently developed exon-capture methods also might allow focused finishing of just coding regions, using ESTs or first-pass shotgun data to drive probe selection. Perhaps by relaxing stringency it these methods might allow capturing exons from a related species -- perhaps a capture array based on dog could capture for fox and such, cat might get lions & tigers -- oh my! With sequencing costs falling so rapidly for a draft genome, I’d probably vote to go for very broad coverage of as many genomes as possible. A lot of information can be gleaned from low-pass information, and the finishing will be much cheaper tomorrow than it is today.

The recently developed exon-capture methods also might allow focused finishing of just coding regions, using ESTs or first-pass shotgun data to drive probe selection. Perhaps by relaxing stringency it these methods might allow capturing exons from a related species — perhaps a capture array based on dog could capture for fox and such, cat might get lions & tigers — oh my!

]]> By: Mike http://www.genomicron.evolverzone.com/2007/11/are-you-cat-genome-person-or-dog-genome/comment-page-1/#comment-430 Mike Fri, 02 Nov 2007 04:14:00 +0000 http://www.genomicron.evolverzone.com/2007/11/are-you-a-cat-genome-person-or-a-dog-genome-person/#comment-430 Looking at that NHGRI list makes me embarrassed to be an Australian scientist. Our single marsupial genome effort (2x of Tammar Wallaby) was part funded by the USA (Applied Biosystems and NIH) and not a single cent came from the federal government.<br/><br/>Dog approach or cat approach, I'll take either! Looking at that NHGRI list makes me embarrassed to be an Australian scientist. Our single marsupial genome effort (2x of Tammar Wallaby) was part funded by the USA (Applied Biosystems and NIH) and not a single cent came from the federal government.

Dog approach or cat approach, I’ll take either!

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