Non-coding DNA and night vision.

Ok, check this out!

Seemingly misplaced DNA acts as lenses

Reporting on Solovei et al (2009)

We show that the nuclear architecture of rod photoreceptor cells differs fundamentally in nocturnal and diurnal mammals. The rods of diurnal retinas possess the conventional architecture found in nearly all eukaryotic cells, with most heterochromatin situated at the nuclear periphery and euchromatin residing toward the nuclear interior. The rods of nocturnal retinas have a unique inverted pattern, where heterochromatin localizes in the nuclear center, whereas euchromatin, as well as nascent transcripts and splicing machinery, line the nuclear border. The inverted pattern forms by remodeling of the conventional one during terminal differentiation of rods. The inverted rod nuclei act as collecting lenses, and computer simulations indicate that columns of such nuclei channel light efficiently toward the light-sensing rod outer segments. Comparison of the two patterns suggests that the conventional architecture prevails in eukaryotic nuclei because it results in more flexible chromosome arrangements, facilitating positional regulation of nuclear functions.


1 comment to Non-coding DNA and night vision.

  • The Lorax

    Heard about this on NPR. Its pretty interesting stuff. It was also interesting listening to Flatow keep suggesting that biologists were too stupid to figure it out and needed real scientists to explain it to us (at least that was my take from his statements).

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