ENCODE quote compilation.

Here’s a short compilation I made for use in a recent presentation on ENCODE and the claim that 80% of the human genome is functional. These are quotes from ENCODE project leaders and the senior editor of Nature. It is not surprising that the story presented by the media was that ENCODE had destroyed […]


Critiques of ENCODE in peer-reviewed journals.

There has been lots of talk (including some in the media; see here and here and here) about the Graur et al. (2013) paper in GBE which was critical of ENCODE, much of it focusing on the tone of the paper. While the Graur et al. (2013) paper certainly doesn’t pull any punches in […]


BBC interview with Ewan Birney.

Say what you want about the tone of the Graur et al. (2013) paper in Genome Biology and Evolution, but it has people talking. Including Ewan Birney, the lead scientist of the ENCODE project and the primary spokesperson for ENCODE in the media fiasco describing the “death of junk DNA”. Most recently, Birney was […]


Graur et al. to ENCODE: Zing!

I expect that we will be seeing several harsh critiques of ENCODE’s extraordinary claims about function in the human genome and the equally incredible mega-hype associated with the project. I know of at least one more that is forthcoming from a heavy-hitter in the field, but as a snarky smackdown, it will be very […]


Max Libbrecht on ENCODE’s results regarding junk DNA.

Max Libbrecht is a PhD student at the University of Washington, and was one of the several hundred researchers involved in the ENCODE project. I have already mentioned Max because of his important comments on ENCODE and junk DNA elsewhere on the interwebs. I mentioned that he would be welcome to write a guest […]


ENCODE spokesperson: 40%, not 80%.

Here’s a very interesting quote, provided by Faye Flam at Knight Science Journalism. (Emphasis mine)

I decided … I would go back to ENCODE biologist John Stamatoyannopoulos, who was quoted in the first wave of news. He said he thought the skeptics hadn’t fully understood the papers, and that some of the activity measured […]


Student ENCODE authors show the way.

Some of the more prominent figures in the ENCODE project, such as Ewan Birney and John Stamatoyannopoulos, have been making statements in the media that exacerbate the hype surrounding the ENCODE results and the infamous claim that “80% of the DNA in the genome is functional”.  For the most part, I have been criticizing […]


More ENCODE videos.

In addition to the cringe-inducing cartoon sponsored by Nature, here are some other videos that have been put out about the ENCODE results. You tell me who you think is responsible for propagating the claim that ENCODE found that “80% of the genome is functional” and that it has overturned the notion of “junk […]


Comments on Birney’s blog.

Ewan Birney, lead coordinator of ENCODE, has a blog. I thought I might re-post a couple of comments from there on here.

First, a weird criticism of me from someone calling himself “TheMayan”. He has written similar things in the comments on my blog. (Don’t you just love the confidence that a pseudonym provides?)

[…]


Good reads about ENCODE.

For an antidote to the massive hype surrounding ENCODE, have a look at these excellent pieces:

The ever deepening mystery of the human genome by Linda Geddes (New Scientist) and be sure to see this editorial: Don’t junk the ‘junk DNA’ just yet

Most of what you read was wrong: how press releases rewrote […]